Fluid-structure interaction for functional assessment of ascending aortic aneurysms

A biomechanical-based approach toward clinical practice

Research Highlights

CFD Model Workflow
CFD modelling of ascending thoracic aorta aneurysm with patient-specific wall displacement
FSI Analysis
Fluid-Structure Interaction analysis: Pre-processing pipeline and in-silico comparison
Experimental Setup
Experimental validation: Pulse duplicator system and DIC measurements
3D Segmentation
Patient-specific aorta segmentation from CT angiography
4D Flow MRI
4D Flow MRI hemodynamic measurements and flow quantification

Project Overview

Reference
PTDC/EMD-EMD/1230/2021
DOI
10.54499/PTDC/EMD-EMD/1230/2021
Budget
248,152.25 €
Duration
January 2022 – January 2025
PI / Co-PI
José Xavier (NOVA-SST) / José Fragata (NMS-FCM)
Keywords
Advanced computational modelling Ascending aortic aneurysm Hemodynamic Biological tissue

Partner Institutions

Institution 1
NOVA.ID.FCT – Associação para a Inovação e Desenvolvimento da FCT
Institution 2
NMS-FCM – NOVA Medical School | Faculdade de Ciências Médicas
Institution 3
INEGI – Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial
Institution 4
CEMAPRE-ISEG – Universidade de Lisboa
International
Center for Biomedical and Healthcare Engineering, MINES Saint-Étienne, France (Stéphane Avril)

Funding

This project is funded by the Portuguese Foundation for Science and Technology (FCT) under the programme "Projetos de Investigação Científica e Desenvolvimento Tecnológico (IC&DT)" through national funds.